Prevention of intraventricular haemorrhage by fresh frozen plasma.

Prevention of intraventricular haemorrhage by fresh frozen plasma.

Seventy three preterm infants weighing less than 1500 g or less than 32 weeks' gestation, or both, were allocated randomly to treatment (fresh frozen plasma 10 ml/kg on admission and at 24 hours of age) or control groups. Fifteen (41%) out of 37 control patients sustained intraventricular haemorrhage compared with five (14%) of 36 patients receiving treatment (X2 = 5.24, P = 0.022). No differen...

Fresh frozen plasma induced thrombocytopenia

Transfusions of blood products are common in medical practice and can be lifesaving in certain situations. Potentially life threatening reactions could occur and physicians should be alerted. Here we describe a case of thrombocytopenia that was induced by transfusion of fresh frozen plasma (FFP). A 52 years old male presented to the emergency department after two episodes of hematochezia that r...

management of castor bean seed-associated intraventricular hemorrhage with fresh frozen plasma: a case report

conclusions intraventricular hemorrhage followed by comatose state is a rare finding of the castor bean seed ingestion. the patient’s condition improved dramatically after ffp transfusion. introduction castor bean seed is used to control some medical conditions including diabetes mellitus due to popular belief in its effectiveness. however it may cause severe poisoning in humans and animals and...

Avoiding the misuse of fresh frozen plasma.

Haemodilution-induced profibrinolytic state is mitigated by fresh-frozen plasma: implications for early haemostatic intervention in massive haemorrhage.

BACKGROUND Fibrinolysis contributes to coagulopathy after major trauma and surgery. We hypothesized that progressive haemodilution is responsible, at least in part, for increased fibrinolytic tendency of blood clot. METHODS The study was performed in two parts. First, whole blood (WB) samples collected from six healthy, consented volunteers were diluted in vitro with either saline or fresh-fr...